Origin of AIDS

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چکیده

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The Origin of AIDS

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The major cause of acquired immune deficiency syndrome (AIDS) is human immunodeficiency virus type 1 (HIV-1). We have been using evolutionary comparisons to trace (i) the origin(s) of HIV-1 and (ii) the origin(s) of AIDS. The closest relatives of HIV-1 are simian immunodeficiency viruses (SIVs) infecting wild-living chimpanzees (Pan troglodytes troglodytes) and gorillas (Gorilla gorilla gorilla...

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T he concept of AIDS as a zoonosis stems from studies that traced HIV origins to two simian species in West and Central Africa—an idea that was reinforced by reports in highprofile journals. Although the simian origin of HIV and other human retroviruses such as human T cell leukemia virus and human foamy viruses is not in dispute, the hypothesis that simian retroviral infections are zoonoses is...

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ژورنال

عنوان ژورنال: Nature

سال: 1985

ISSN: 0028-0836,1476-4687

DOI: 10.1038/318100a0